Progeria
is one of the most dreadful genetic diseases of the Earth. The modern word
Progeria has been taken from the Greek “Progeros” which indicates “Premature
old”.
This
disease was first presented before the world by Dr.Jonathan Hutchinson in 1886
and Dr. Gilford in 1897 and with their names the disease has been given such
name as HGPS.
This
fatal disease has different symptoms. The early signs of aging are big symptoms
of this disease. Besides there are many syndrome prevailing of this disease
such as decreasing of growth, short size, loss of body fat , fall of hair,
cardio and heart disease , stiffness in joint area, stroke etc .
Among every 4 to 5
billion newborn babies, one baby is affected by this disease in UK. The
countries like Argentina, Israel, Armenia, and Austria. Canada, Australia,
England etc have already reported the vicious impact of progeria. The Progeria
affected patients do not live long and these types of patients generally die
between the ages of 8 to 21.
Progeria leads to release” Lamin A” protein and this protein helps
the nucleus to be unstable.This instability accelerate the process of aging.
Most of the physician affirmed that Progeria is not a hereditary disease. It is
found that progeria syndromes pass to one generation to another in about 1 in
100 cases.
Progeria
can be recognized through genetic test or by watching the symptoms
FITS
(FARNESYLTRANSFERASE) might give a new structure to the unstable nucleus which
supposed to be the main cause of progeria. An FITS testing was taken
among 13 mice and only one was died of 105 days UCLA study.
“This study gives us pieces of information critical to our movement toward clinical trials in children with progeria."-spoken by Dr. Leslie Gordon.But what is most unfortunate is that there is no special treatment available in the universe for this dreadful disease.
